ISO 8 Clean Room is defined as an area of the community where environmental control is introduced and maintained to carry out clean tasks or other specialized operations which may generate contaminants that could affect the health of those interested in the area. An SO 8 Clean Room is a developed enclosed environment in which microorganisms are at a density controlled to an accepted limit. ISO 8 is not as clean as ISO 5 or ISO 4, however, it is cleaner than other conditions as ISO 5 or ISO 4 means ultra clean areas or clean rooms.

Due to the complexity of the external environment, it is not easy to realize the actual cleanliness of Fab. The main sources of contamination are particles, metal elements and organic matter from personnel activities. Particles and metal elements from equipment operation. Particles, metal elements and organic matter from raw and auxiliary materials. Particles of oxidized organic matter from operating methods. And particles from the workshop environment. Of these, particulate matter accounts for about 37-70%, liquid particles for about 10-30%, and microorganisms for about 5-20%.

Pass Box is not only a window, but also has the function of isolation. Transfer window is a kind of auxiliary equipment of clean room, mainly used for transferring small items between clean area and clean area, non-clean area and clean area. 

As a critical environment in the medical and pharmaceutical industries, the cleanliness of cleanrooms is directly related to product quality and safety. However, the greatest source of contamination in Cleanrooms often comes from the users themselves, especially microorganisms shed from the skin. These microorganisms can be spread through the airflow and pose a threat to the clean environment. Therefore, controlling microbial contamination and taking effective disinfection measures are the core tasks of cleanroom management.