The pharmaceutical and food industries along with medical device producers must follow the standardized Good Manufacturing Practice (GMP) for their Cleanrooms which establishes particular hygiene and cleanliness requirements.

Pharmaceutical Cleanrooms operate as essential components of contemporary biopharmaceutical companies to manufacture highly pure biopharmaceuticals and medical devices at high quality standards. The strict requirements for product sensitiveness dictate the pharmaceutical cleanrooms need exceptionally high cleanliness standards.

Special attention is needed when cleaning cleanroom floors as they need to maintain a high standard of environmental cleanliness. There  are 3 methods exist different recognized techniques for cleanroom maintenance.

ISO 8 Clean Room is defined as an area of the community where environmental control is introduced and maintained to carry out clean tasks or other specialized operations which may generate contaminants that could affect the health of those interested in the area. An SO 8 Clean Room is a developed enclosed environment in which microorganisms are at a density controlled to an accepted limit. ISO 8 is not as clean as ISO 5 or ISO 4, however, it is cleaner than other conditions as ISO 5 or ISO 4 means ultra clean areas or clean rooms.